we are China factory sell Chemicals Ethyl methanesulfonate CAS 62-50-0,it is colorless liquid .we have factory to produce the Ethyl methanesulfonate with best quality ,each day can produce the 5 ton Ethyl methanesulfonate , contact me if you want to order the Ethyl methanesulfonate from CHina Ethyl methanesulfonate supplier in China with best price ~~
contact me if you need order the Ethyl methanesulfonate
email daisy@crovellbio.com
whatsapp +86 19930503252
wickrme daisylang
Product Information
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Product Name
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Ethyl methanesulfonate
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CAS NO.
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62-50-0
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Formula
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C3H8O3S
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Molecular Weight
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124.16
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Appearance
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White
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Application
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Pharmaceutical/Syntheses Material Intermediates
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Ethyl methanesulfonate (EMS) is a mutagenic, teratogenic, and possibly carcinogenic organic compound with formula C3H8SO3. It produces random mutations in genetic material by nucleotide substitution; particularly by guanine alkylation. This typically produces only point mutations. It can induce mutations at a rate of 5x10−4 to 5x10−2 per gene without substantial killing. The ethyl group of EMS reacts with guanine in DNA, forming the abnormal base O-6-ethylguanine. During DNA replication, DNA polymerases that catalyze the process frequently place thymine, instead of cytosine, opposite O-6-ethylguanine. Following subsequent rounds of replication, the original G:C base pair can become an A:T pair (a transition mutation). This changes the genetic information, is often harmful to cells, and can result in disease.
EMS is often used in genetics as a mutagen. Mutations induced by EMS can then be studied in genetic screens or other assays. |
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contact me if you need order the Ethyl methanesulfonate from China supplier
email daisy@crovellbio.com
whatsapp +86 19930503252
wickrme daisylang
